This test can show the effectiveness and safety of a vaccine. In order to understand why different people respond to vaccinations differently in terms of protection against and spreading it to others, the field of vaccinomics investigates genetic factors.
Vaccinomics is the application of multidimensional science to the understanding of biologic and immunologic vaccine responses and variability in immune responses. Vaccine programmes typically give everyone the same dose at the same intervals. Given that we know people have different responses, vaccinomics could inform better vaccine design, vaccine schedules and even personalised vaccines to ensure effective responses for everyone.
Some vaccines, e.g. for influenza, are administered to different age groups according to the level of immune response. Vaccinomics could improve our understanding of which vaccines are more suitable for these age groups.
Individuals may respond differently to a vaccine because of variations in immune response due to sex or ethnic background. For example, women may benefit from a smaller vaccine dose, reducing the risk of side-effects while experiencing the same protection from disease.
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